/* ==========================================================================
   penicilline.com — feuille de style principale
   Design : ressource éditoriale scientifique. Signature : la zone d'inhibition
   (l'anneau clair autour d'une colonie de Penicillium) rendue en pur CSS.
   Zéro police externe, zéro requête bloquante — pensé pour 100/100 PageSpeed.
   ========================================================================== */

/* ---------- Tokens ---------- */
:root {
  --bg:          #f1f4ef;   /* gélose pâle, teinté vert */
  --surface:     #ffffff;
  --surface-alt: #e9eee7;
  --ink:         #14201b;   /* vert forêt quasi noir */
  --muted:       #566159;
  --accent:      #0e6b4f;   /* vert Penicillium */
  --accent-dark: #093f2e;
  --accent-soft: #dcebe4;
  --gold:        #b0842d;   /* rappel « âge d'or » / Nobel, usage rare */
  --border:      #d6ddd3;
  --shadow:      0 1px 2px rgba(20,32,27,.06), 0 8px 24px -12px rgba(20,32,27,.18);

  --serif: Georgia, "Iowan Old Style", "Times New Roman", serif;
  --sans:  system-ui, -apple-system, "Segoe UI", Roboto, Helvetica, Arial, sans-serif;

  --maxw: 68rem;
  --measure: 42rem;
  --radius: 4px;
  --space: clamp(3rem, 7vw, 5.5rem);
}

/* ---------- Reset ---------- */
*, *::before, *::after { box-sizing: border-box; }
html { -webkit-text-size-adjust: 100%; scroll-behavior: smooth; }
@media (prefers-reduced-motion: reduce) {
  html { scroll-behavior: auto; }
  *, *::before, *::after { animation: none !important; transition: none !important; }
}
body {
  margin: 0;
  background: var(--bg);
  color: var(--ink);
  font-family: var(--sans);
  font-size: 1.0625rem;
  line-height: 1.65;
  -webkit-font-smoothing: antialiased;
  text-rendering: optimizeLegibility;
}
img, svg { max-width: 100%; height: auto; display: block; }
a { color: var(--accent-dark); text-underline-offset: .18em; text-decoration-thickness: .06em; }
a:hover { color: var(--accent); }
h1, h2, h3, h4 { font-family: var(--serif); font-weight: 700; line-height: 1.15; color: var(--ink); }
:focus-visible { outline: 3px solid var(--accent); outline-offset: 3px; border-radius: 2px; }

/* ---------- Layout helpers ---------- */
.wrap { width: 100%; max-width: var(--maxw); margin-inline: auto; padding-inline: clamp(1.1rem, 4vw, 2.25rem); }
.prose { max-width: var(--measure); }
.prose > * + * { margin-top: 1.1em; }
.prose h2 { font-size: clamp(1.5rem, 3.4vw, 2rem); margin-top: 2.4em; }
.prose h3 { font-size: 1.28rem; margin-top: 1.8em; }
.prose ul, .prose ol { padding-left: 1.3em; }
.prose li + li { margin-top: .4em; }
.skip { position: absolute; left: -999px; top: 0; background: var(--ink); color: #fff; padding: .7em 1.1em; z-index: 100; }
.skip:focus { left: .5rem; top: .5rem; color:#fff; }

/* ---------- Header ---------- */
.site-header {
  position: sticky; top: 0; z-index: 40;
  background: color-mix(in srgb, var(--bg) 86%, transparent);
  backdrop-filter: saturate(1.4) blur(8px);
  border-bottom: 1px solid var(--border);
}
.header-inner { display: flex; align-items: center; justify-content: space-between; gap: 1rem; min-height: 4.25rem; }
.brand { display: inline-flex; align-items: center; gap: .6rem; font-family: var(--serif); font-weight: 700; font-size: 1.28rem; color: var(--ink); text-decoration: none; letter-spacing: -.01em; }
.brand:hover { color: var(--ink); }
.brand .dish { flex: 0 0 auto; }
.brand b { color: var(--accent); font-weight: 700; }

.nav-toggle { position: absolute; width: 1px; height: 1px; opacity: 0; pointer-events: none; }
.nav-btn {
  display: none; align-items: center; gap: .5rem; background: none; border: 1px solid var(--border);
  border-radius: var(--radius); padding: .5rem .7rem; font: inherit; font-size: .95rem; color: var(--ink); cursor: pointer;
}
.nav-toggle:focus-visible ~ .nav-btn { outline: 3px solid var(--accent); outline-offset: 3px; }
.primary-nav ul { list-style: none; display: flex; gap: .3rem; margin: 0; padding: 0; align-items: center; }
.primary-nav a {
  display: inline-block; padding: .5rem .75rem; border-radius: var(--radius);
  color: var(--ink); text-decoration: none; font-size: .97rem; font-weight: 500;
}
.primary-nav a:hover { background: var(--accent-soft); color: var(--accent-dark); }
.primary-nav a[aria-current="page"] { color: var(--accent); box-shadow: inset 0 -2px 0 var(--accent); border-radius: 0; }

@media (max-width: 62rem) {
  .nav-btn { display: inline-flex; }
  .primary-nav {
    position: absolute; left: 0; right: 0; top: 100%; background: var(--surface);
    border-bottom: 1px solid var(--border); box-shadow: var(--shadow);
    max-height: 0; overflow: hidden; visibility: hidden; transition: max-height .25s ease;
  }
  .primary-nav ul { flex-direction: column; align-items: stretch; gap: 0; padding: .5rem 0; }
  .primary-nav a { padding: .85rem clamp(1.1rem, 4vw, 2.25rem); border-radius: 0; }
  .nav-toggle:checked ~ .primary-nav { max-height: 32rem; visibility: visible; }
}

/* ---------- Signature : la boîte de Petri / zone d'inhibition ---------- */
.dish {
  --d: 2rem;
  width: var(--d); height: var(--d); border-radius: 50%;
  background:
    radial-gradient(circle at 50% 50%,
      var(--accent) 0 24%,
      var(--accent-soft) 24% 34%,           /* zone d'inhibition (anneau clair) */
      var(--accent) 34% 40%,
      var(--surface-alt) 40% 100%);
  box-shadow: inset 0 0 0 1px rgba(20,32,27,.12);
}

.hero-dish {
  --d: min(46vw, 20rem);
  position: relative; margin-inline: auto;
  background:
    radial-gradient(circle at 46% 44%,
      #0c5c44 0 15%,
      #127c5b 15% 22%,
      var(--accent-soft) 22% 31%,           /* halo clair : bactéries inhibées */
      #14855f 31% 37%,
      #0f6b4f 37% 46%,
      #cfe0d5 46% 100%);
}
.hero-dish::after {
  content: ""; position: absolute; inset: 0; border-radius: 50%;
  box-shadow: inset 0 0 0 6px var(--surface), inset 0 0 0 7px var(--border);
}

/* ---------- Hero ---------- */
.hero { padding-block: clamp(3rem, 8vw, 6rem) var(--space); }
.hero-grid { display: grid; grid-template-columns: 1.15fr .85fr; gap: clamp(2rem, 5vw, 4rem); align-items: center; }
.eyebrow {
  display: inline-block; font-family: var(--sans); font-size: .78rem; font-weight: 600;
  letter-spacing: .12em; text-transform: uppercase; color: var(--accent); margin-bottom: 1rem;
}
.hero h1 { font-size: clamp(2.1rem, 6vw, 3.6rem); letter-spacing: -.02em; margin: 0 0 1rem; }
.hero p.lead { font-size: clamp(1.1rem, 2.4vw, 1.3rem); color: var(--muted); max-width: 34rem; margin: 0 0 1.8rem; }
.hero-cta { display: flex; flex-wrap: wrap; gap: .8rem; }

@media (max-width: 52rem) {
  .hero-grid { grid-template-columns: 1fr; }
  .hero-dish { --d: min(70vw, 17rem); order: -1; }
}

/* ---------- Buttons ---------- */
.btn {
  display: inline-flex; align-items: center; gap: .5rem; padding: .8rem 1.35rem;
  border-radius: var(--radius); font: inherit; font-weight: 600; font-size: 1rem;
  text-decoration: none; cursor: pointer; border: 1px solid transparent; transition: transform .12s ease, background .2s ease;
}
.btn-primary { background: var(--accent); color: #fff; }
.btn-primary:hover { background: var(--accent-dark); color: #fff; transform: translateY(-1px); }
.btn-ghost { background: transparent; color: var(--accent-dark); border-color: var(--border); }
.btn-ghost:hover { background: var(--surface); border-color: var(--accent); }

/* ---------- Sections ---------- */
.section { padding-block: var(--space); }
.section-alt { background: var(--surface-alt); border-block: 1px solid var(--border); }
.section-head { max-width: 40rem; margin-bottom: 2.5rem; }
.section-head .eyebrow { margin-bottom: .6rem; }
.section-head h2 { font-size: clamp(1.7rem, 4vw, 2.5rem); letter-spacing: -.01em; margin: 0 0 .6rem; }
.section-head p { color: var(--muted); margin: 0; font-size: 1.1rem; }

/* ---------- Cluster cards ---------- */
.cluster-grid { display: grid; grid-template-columns: repeat(auto-fit, minmax(16rem, 1fr)); gap: 1.25rem; }
.cluster {
  position: relative; background: var(--surface); border: 1px solid var(--border);
  border-radius: 10px; padding: 1.6rem 1.5rem 1.5rem; box-shadow: var(--shadow);
  display: flex; flex-direction: column; transition: transform .15s ease, border-color .2s ease;
}
.cluster:hover { transform: translateY(-3px); border-color: var(--accent); }
.cluster .num { font-family: var(--serif); font-size: .95rem; color: var(--gold); font-weight: 700; letter-spacing: .04em; }
.cluster h3 { font-size: 1.3rem; margin: .5rem 0 .5rem; }
.cluster h3 a { text-decoration: none; color: var(--ink); }
.cluster h3 a:hover { color: var(--accent); }
.cluster h3 a::after { content: ""; position: absolute; inset: 0; }
.cluster p { color: var(--muted); font-size: .98rem; margin: 0 0 1.1rem; flex: 1; }
.cluster .count { font-size: .85rem; font-weight: 600; color: var(--accent); }

/* ---------- Article list (pillar pages) ---------- */
.article-list { list-style: none; padding: 0; margin: 0; display: grid; gap: .2rem; }
.article-list li { border-bottom: 1px solid var(--border); }
.article-list a {
  display: flex; align-items: baseline; gap: 1rem; padding: 1.05rem .25rem;
  text-decoration: none; color: var(--ink);
}
.article-list a:hover { color: var(--accent); }
.article-list a:hover .art-title { text-decoration: underline; text-underline-offset: .2em; }
.article-list .art-idx { flex: 0 0 auto; font-family: var(--serif); color: var(--gold); font-weight: 700; width: 2ch; text-align: right; }
.article-list .art-title { font-weight: 500; }
.article-list .art-desc { display: block; color: var(--muted); font-size: .92rem; font-weight: 400; margin-top: .15rem; }

/* ---------- Feature / trust strip ---------- */
.trust { display: grid; grid-template-columns: repeat(auto-fit, minmax(14rem, 1fr)); gap: 1.5rem; }
.trust .item h3 { font-size: 1.1rem; margin: 0 0 .35rem; }
.trust .item p { color: var(--muted); font-size: .96rem; margin: 0; }
.trust .item .ic { width: 2.2rem; height: 2.2rem; color: var(--accent); margin-bottom: .7rem; }

/* ---------- Breadcrumb ---------- */
.crumbs { font-size: .88rem; color: var(--muted); padding-block: 1.1rem .2rem; }
.crumbs ol { list-style: none; display: flex; flex-wrap: wrap; gap: .4rem; margin: 0; padding: 0; }
.crumbs li::after { content: "/"; margin-left: .4rem; color: var(--border); }
.crumbs li:last-child::after { content: ""; }
.crumbs a { color: var(--muted); text-decoration: none; }
.crumbs a:hover { color: var(--accent); text-decoration: underline; }

/* ---------- Article header ---------- */
.article-head { padding-block: 1.5rem var(--space); border-bottom: 1px solid var(--border); }
.article-head h1 { font-size: clamp(1.9rem, 5vw, 3rem); letter-spacing: -.02em; max-width: 22ch; margin: .4rem 0 1rem; }
.article-head .lead { font-size: 1.2rem; color: var(--muted); max-width: var(--measure); margin: 0; }
.article-meta { display: flex; flex-wrap: wrap; gap: 1rem; margin-top: 1.5rem; font-size: .9rem; color: var(--muted); }
.article-meta span { display: inline-flex; align-items: center; gap: .4rem; }

/* ---------- Callouts ---------- */
.callout {
  border-left: 4px solid var(--accent); background: var(--accent-soft);
  padding: 1.1rem 1.3rem; border-radius: 0 var(--radius) var(--radius) 0; margin: 1.6rem 0;
}
.callout.warn { border-color: var(--gold); background: #f7efdd; }
.callout p { margin: 0; }
.callout strong { color: var(--accent-dark); }

/* ---------- Key facts box ---------- */
.keybox { background: var(--surface); border: 1px solid var(--border); border-radius: 10px; padding: 1.4rem 1.5rem; box-shadow: var(--shadow); }
.keybox h2 { font-size: 1.15rem; margin: 0 0 .8rem; }
.keybox ul { margin: 0; padding-left: 1.2rem; }
.keybox li { margin: .35rem 0; }

/* ---------- FAQ (native <details>) ---------- */
.faq details { border-bottom: 1px solid var(--border); }
.faq summary {
  cursor: pointer; list-style: none; padding: 1.1rem 2rem 1.1rem 0; position: relative;
  font-family: var(--serif); font-size: 1.12rem; font-weight: 700; color: var(--ink);
}
.faq summary::-webkit-details-marker { display: none; }
.faq summary::after { content: "+"; position: absolute; right: .2rem; top: .95rem; font-size: 1.5rem; color: var(--accent); font-family: var(--sans); }
.faq details[open] summary::after { content: "\2013"; }
.faq details p { margin: 0 0 1.2rem; color: var(--muted); }

/* ---------- Contact form ---------- */
.form-grid { display: grid; gap: 1.1rem; max-width: 34rem; }
.field { display: grid; gap: .35rem; }
.field label { font-weight: 600; font-size: .95rem; }
.field input, .field textarea, .field select {
  font: inherit; padding: .7rem .85rem; border: 1px solid var(--border);
  border-radius: var(--radius); background: var(--surface); color: var(--ink); width: 100%;
}
.field input:focus, .field textarea:focus { outline: 2px solid var(--accent); border-color: var(--accent); }
.field textarea { min-height: 8rem; resize: vertical; }
.form-note { font-size: .85rem; color: var(--muted); }

/* ---------- Related / next steps ---------- */
.related { display: grid; grid-template-columns: repeat(auto-fit, minmax(15rem, 1fr)); gap: 1rem; }
.related a {
  display: block; background: var(--surface); border: 1px solid var(--border); border-radius: 8px;
  padding: 1.1rem 1.2rem; text-decoration: none; color: var(--ink); transition: border-color .2s ease;
}
.related a:hover { border-color: var(--accent); }
.related a .k { display: block; font-size: .78rem; text-transform: uppercase; letter-spacing: .1em; color: var(--accent); margin-bottom: .3rem; }
.related a .t { font-family: var(--serif); font-weight: 700; }

/* ---------- CTA band ---------- */
.cta-band { background: var(--accent-dark); color: #eaf3ee; text-align: center; }
.cta-band h2 { color: #fff; font-size: clamp(1.6rem, 4vw, 2.3rem); margin: 0 0 .7rem; }
.cta-band p { color: #cfe3d8; max-width: 34rem; margin: 0 auto 1.6rem; }
.cta-band .btn-ghost { color: #fff; border-color: rgba(255,255,255,.4); }
.cta-band .btn-ghost:hover { background: rgba(255,255,255,.1); border-color: #fff; }

/* ---------- Footer ---------- */
.site-footer { background: var(--ink); color: #c4cec8; padding-block: var(--space) 2rem; margin-top: var(--space); }
.footer-grid { display: grid; grid-template-columns: 1.4fr repeat(3, 1fr); gap: 2rem; }
.site-footer h4 { color: #fff; font-family: var(--sans); font-size: .82rem; text-transform: uppercase; letter-spacing: .1em; margin: 0 0 1rem; }
.site-footer ul { list-style: none; margin: 0; padding: 0; }
.site-footer li { margin: .5rem 0; }
.site-footer a { color: #c4cec8; text-decoration: none; font-size: .95rem; }
.site-footer a:hover { color: #fff; text-decoration: underline; }
.footer-brand .brand { color: #fff; }
.footer-brand p { font-size: .92rem; max-width: 26rem; color: #9fb0a8; }
.footer-bottom { border-top: 1px solid rgba(255,255,255,.12); margin-top: 2.5rem; padding-top: 1.5rem; display: flex; flex-wrap: wrap; gap: 1rem; justify-content: space-between; font-size: .85rem; color: #8fa199; }
.footer-bottom a { color: #8fa199; }

@media (max-width: 52rem) { .footer-grid { grid-template-columns: 1fr 1fr; } }
@media (max-width: 34rem) { .footer-grid { grid-template-columns: 1fr; } }

/* ---------- Utilities ---------- */
.center { text-align: center; }
.mt-0 { margin-top: 0; }
.disclaimer-mini { font-size: .85rem; color: var(--muted); border-top: 1px dashed var(--border); padding-top: 1.2rem; margin-top: 2.5rem; }